Science at Patana follows the English National Curriculum and provides three major areas of study: life and living processes, materials and their properties and physical processes. The subject is concerned with encouraging children to investigate the world around them by using scientific techniques and to gain a greater understanding of themselves and the world.

In the Primary School children are provided with an environment where they can develop the skills necessary to become "young scientists". These include observation, discussion, identifying, measuring and hypothesising. Exploration and communication are encouraged and science is related to everyday life.

This approach is developed further with increased emphasis on hypothesising, planning, testing, finding results and recording. Children learn to think scientifically by using this process through a variety of explorations and investigations. For example, they explore how plants grow, what forces affect the motion of a toy car, what electricity is, how shadows are made and how sounds are made, so that they build up concepts of principles behind all of these and more. Most importantly they learn through their experience of first hand testing and observing.

In the Secondary School Year 7 and Year 8 students are taught via a number of various themes related to life and living processes, forces, energy, the environment, chemicals and chemical reactions, and materials. The course on which themes are based is "Spotlight Science".

The Year 9 curriculum is taught in the separate areas of biology, chemistry and physics, with individual subject teachers. It is the foundation year for IGCSE courses after which the students have various option choices open to them. All students study Co-ordinated Sciences (double award) IGCSE course for their Year 10 and Year 11 study programme. The Co-ordinated Sciences IGCSE course offers a broad and balanced curriculum covering the three sciences. It is ideal preparation for taking any of the senior science courses. Students may also choose to study Environmental Management at IGCSE.

The Senior Studies programme includes IB Higher and Standard Level courses in Physics, Chemistry and Biology. Environmental Systems and Societies is offered as a Standard Level. A student is able to take a maximum of two Sciences in this programme.

Science facilities in the Secondary School include ten laboratories with associated specialist areas. Each laboratory has good resources for science studies up to pre-university level.